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The children's version includes 32 items whereas the teenagers’ version includes 41 items.It consists of seven subscales related to the body image, the cognitive functioning, family relationships, prospects for life, physical functioning and symptoms, psychological functioning and social functioning. Level 5 refers to the highest level of Qo L and to the minimal negative effect of cancer and its treatment in the Qo L.

Minneapolis-Manchester Quality of Life Instrument was used for data collection from July 2010 to December 2012.Many studies have checked validity and reliability of the Minneapolis-Manchester Qo L questionnaire (19–21). carried out on 162 children and 268 adolescents with cancer, internal consistency reliability Cronbach's was found to be 0.72 in the children's version (c8–12 years old) in all subscales, and 0.78 in the adolescents version (aged 13–20 years), in six of the seven subscales (22).Prior to the translation, we obtained permission to use directly from Smita Bhatia by email.At the second stage, the Greek translation for each version was given to two independent translators for reverse translation.At the third stage, the reverse translation for each version of the tools and their original English versions were distributed to a group of experts (two Professors from the University of Athens, two Pediatric Oncologists and two oncology nurses).